|
T6347 |
Ki16198
|
|
LPA Receptor
,
LPL Receptor
|
|
Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively, shows weaker inhibition for LPA2, no activ... |
|
T12580 |
PTUPB
|
|
COX
,
Epoxide Hydrolase
|
|
PTUPB is a potent and dual inhibitor of sEH and COX-2 enzymes(IC50 of 0.9 nM and 1.26 μM, respectively). |
|
T15367 |
Gadoxetate Disodium
|
Gd-EOB-DTPA Disodium,ZK 139834 |
Others
|
|
Gadoxetate Disodium is used to evaluate focal liver lesions, such as hepatocellular carcinoma or liver metastasis on T1-weighted imaging. It is a contrast agent in magnetic resonance imaging (MRI) of the hepatobiliary sy... |
|
T10904 |
CWP232228
|
|
Wnt/beta-catenin
|
|
CWP232228, a potent and selective Wnt / β-catenin signaling inhibitor, antagonizes the binding of β-catenin to T-cell factor (TCF) in the nucleus. CWP232228 inhibits the formation and metastasis of tumors by inhibiting t... |
|
T9398 |
NSC 73150
|
NSC 97967 |
Others
|
|
6-methyl-2-[2-[(E)-(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]hydraziny l]-1H-pyrimidin-4-one (NSC 73150) is a pyrimidine derivative with antitumor activity. Preclinical studies have shown that it inhibits the growth of a... |
|
T77743 |
TT-012
|
|
Others
|
|
TT-012 has anti-tumor activity, selectively binds dynamic MITF and disrupts the dimer formation and DNA binding of the latter. TT-012 can inhibit the transcription of MITF in B16F10 melanoma cells. TT-012 inhibited the g... |
|
T75089 |
Selachyl alcohol
|
|
|
|
Selachyl alcohol, an alkylglycerol compound found in shark liver oil, exhibits properties as an orally active antihypertensive agent with similar activities to antihypertensive neutral renomedullary lipid (ANRL). It is k... |
|
T35587 |
Ganglioside GD1a mixture (sodium salt)
|
Ganglioside B1 |
|
|
Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. [1] It can be shed from the surface of tumor cells into the microenvironment where it i... |
|
T79452 |
Tubulin/HDAC-IN-2
|
|
|
|
Tubulin/HDAC-IN-2 (Compound II-19k) is a dual inhibitor targeting Tubulin and HDAC, exhibiting IC50 values of 0.403 μM for HDAC1, 0.591 μM for HDAC2, 3.552 μM for HDAC3, and 0.459 μM for HDAC6. The compound induces G2 ph... |
